CONTEMPORARY DIAGNOSTIC CONSEPTS IN VITILIGO: CLINICAL EVALUATION, BIOMARKER IDENTIFICATION AND ADVANCED IMAGING TECHNOLOGIES
Received: 2026-07-16 04:15:14
Published: 2026-04-18
Abstract
Vitiligo is a multifactorial depigmenting skin disorder characterized by the progressive disappearance of melanocytes resulting in sharply defined hypopigmented or depigmented lesions. Increasing knowledge about autoimmune mechanisms, oxidative stress pathways, and genetic susceptibility has significantly transformed diagnostic approaches during the last decade. Modern dermatological practice emphasizes early detection of disease activity and differentiation from similar pigmentary abnormalities through non-invasive imaging techniques, laboratory biomarker evaluation, and digital analytical systems. This review discusses current diagnostic principles, clinical manifestations, prognostic determinants, and emerging technological solutions used for accurate evaluation of vitiligo.
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